Two well-known tech companies had a special way of doing things that allowed them to produce excellent products. Now, we are following a different path. Can we change and try a new, friendlier approach?
Once semiconductor companies master the fabrication of micro-electromechanical systems (which they have), the next step is to master nano-electromechanical systems (which they are starting to).
Even without the hand holding of expensive, sophisticated simulation software, you can design an analog IC. Let's proceed.
Some classics have their time and then fade, but others are still with us; the analog peak detector is still going strong.
Data transmission that is done per the RS485 convention can be accomplished without a ground or circuit-common connection. The RS485 transmitters and receivers will tolerate significant differences in ground potential.